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Fig. 8 | Epigenetics & Chromatin

Fig. 8

From: The N-terminal dimerization domains of human and Drosophila CTCF have similar functionality

Fig. 8

Genome browser tracks for representative regions with occupancy of dCTCFwtHA, dCTCFΔ80–170-HA, dCTCFhN. The dCTCF motif track is shown for convenience. Protein-coding genes are depicted in dark blue, lncRNA-coding genes are shown in yellow, and arrowheads indicate promoters. (A) Regions with CTCFwtHA, CTCFd80–170-HA, and dCTCFhN occupancy, with peaks confirmed by motifs. (B) Regions lacking CTCFd80–170-HA binding with peaks confirmed by motifs. Red dashed lines mark the boundaries of the regulatory iab domains. (C) Regions with CTCFwtHA, CTCFd80–170-HA, dCTCFhN occupancy, and CP190 enrichment, lacking the dCTCF DNA binding motif

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