Fig. 6

Comparative analysis of compartments A/B between both lens and ES cells. (a) Median gene expression of genes in A/B compartments in of lens epithelial (median: A = 1.26, B = 0.332) and lens fiber cells (median: A = 0.854, B = 0.054). (b) Genome wide compartment analysis. Two Pax6 (c) and Rarb (d) loci are used to illustrate regional compartmental changes. Positive Eigen values shown in orange are denoted as “Compartment A”, whereas negative Eigen values shown in purple are denoted as “Compartment B”. Green peaks are show significant differences in A/B compartmental changes between cell types (Log 10 P adjusted of significant Mahalanobis peaks)