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Table 1 Genes encoding components of KAT complexes are consistently down-regulated by HDACi

From: Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response

  1. The table shows the fold change between 0 and 120 min of genes encoding KAT complex proteins at the inhibitor concentrations shown. Statistically significant changes (ANOVA, fold change >1.5, FDR <10 %) are shaded in green. No KATs were significantly down-regulated by 0.2 mM VPA.
  2. * ING5 is reported to be a member of the HBO1 and MOZ/MORF complexes.